(2 references)-
- 抗原 See all CD59 抗体
- CD59
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适用
- 人, Pig
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD59 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- The antibody MEM-129 reacts with CD59 (Protectin), a 18-20 kDa glycosylphosphatidylinositol (GPI)-anchored extracellular glycoprotein expressed on all hematopoietic cells, it is widely present on cells in all tissus.
- 交叉反应 （详细）
- Human, Porcine
- 纯化方法
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Human peripheral blood lymphocytes
- 克隆位点
- MEM-129
- 亚型
- IgM
- Top Product
- Discover our top product CD59 Primary Antibody
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anti-CD59 (CD59) (AA 31-111) antibody
CD59 适用: 人 FACS, WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8D2B8 unconjugated
anti-CD59 (CD59) (AA 74-110) antibodyCD59 适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB56691 unconjugated
anti-CD59 (CD59) antibodyCD59 适用: 人 FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-43 unconjugated
anti-CD59 (CD59) antibodyCD59 适用: 人, 小鼠 FACS, WB, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-43-5 unconjugated
anti-CD59 (CD59) (AA 31-111) antibodyCD59 适用: 人 FACS, WB, IHC, ELISA, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-CD59 (CD59) (AA 23-105) antibodyCD59 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD59 (CD59) (AA 1-128) antibodyCD59 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-CD59 (CD59) (AA 52-100) antibodyCD59 适用: 人 FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD59 (CD59) (AA 26-102) antibodyCD59 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD59 (CD59) antibodyCD59 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Functional application: The antibody MEM-129 activates T cells.
Flow cytometry: Recommended dilution: 1-4 μg/mL. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- HEPES buffered saline (HBS), pH 7.0
- 储存液
- Azide free
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterol." in: The Journal of biological chemistry, Vol. 272, Issue 31, pp. 19242-7, (1997) (PubMed).
: "CD64/Fc gamma RI is a granulo-monocytic lineage marker on CD34+ hematopoietic progenitor cells." in: Blood, Vol. 85, Issue 9, pp. 2402-13, (1995) (PubMed).
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: "Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterol." in: The Journal of biological chemistry, Vol. 272, Issue 31, pp. 19242-7, (1997) (PubMed).
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- 抗原
- CD59
- 别名
- CD59 (CD59 产品)
- 别名
- 16.3A5 antibody, 1F5 antibody, EJ16 antibody, EJ30 antibody, EL32 antibody, G344 antibody, HRF-20 antibody, HRF20 antibody, MAC-IP antibody, MACIF antibody, MEM43 antibody, MIC11 antibody, MIN1 antibody, MIN2 antibody, MIN3 antibody, MIRL antibody, MSK21 antibody, p18-20 antibody, Cd59a antibody, Cd59b antibody, MACIP antibody, CD59 molecule (CD59 blood group) antibody, CD59 molecule antibody, CD59 antibody, Cd59 antibody
- 背景
- CD59 Molecule,CD59 (protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.,MACIF, MAC-IP, protectin, MIRL, HRF-20, HRF20, 1F5, MIN
- 基因ID
- 966
- UniProt
- P13987
- 途径
- Complement System
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