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CD55 抗体

CD55 适用: 人, Non-Human Primate WB, FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-118 unconjugated
产品编号 ABIN94183
发货至: 中国
  • 抗原 See all CD55 抗体
    CD55 (Complement Decay-Accelerating Factor (CD55))
    适用
    • 109
    • 35
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    人, Non-Human Primate
    宿主
    • 69
    • 66
    • 6
    • 6
    • 3
    • 1
    • 1
    小鼠
    克隆类型
    • 81
    • 69
    • 2
    单克隆
    标记
    • 72
    • 17
    • 16
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD55 antibody is un-conjugated
    应用范围
    • 97
    • 76
    • 47
    • 39
    • 33
    • 25
    • 15
    • 15
    • 14
    • 12
    • 9
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain extracellular glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.
    交叉反应 (详细)
    Human, Non-Human Primates
    纯化方法
    Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    HPB-ALL human T cell line
    克隆位点
    MEM-118
    亚型
    IgM
    Top Product
    Discover our top product CD55 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 10 μg/mL.
    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).

  • 抗原
    CD55 (Complement Decay-Accelerating Factor (CD55))
    别名
    CD55 (CD55 产品)
    别名
    CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody
    背景
    CD55 Molecule (Cromer blood group),CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.,DAF, CROM, CHAPLE
    基因ID
    1604
    UniProt
    P08174
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity
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