CD55 抗体
Quick Overview for CD55 抗体 (ABIN94183)
抗原
See all CD55 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-Hu CD55 Purified
-
特异性
- The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain extracellular glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.
-
交叉反应 (详细)
- Human, Non-Human Primates
-
纯化方法
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
-
纯度
- > 95 % (by SDS-PAGE)
-
免疫原
- HPB-ALL human T cell line
-
亚型
- IgM
-
-
-
-
应用备注
-
Flow cytometry: Recommended dilution: 10 μg/mL.
Immunohistochemistry (paraffin sections): Heat-mediated antigen retrieval, recommended dilution: 10 μg/mL. -
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Do not freeze.
-
储存条件
- 4 °C
-
储存方法
- Store at 2-8°C. Do not freeze.
-
-
-
Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).
: "
-
Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).
-
- CD55 (Complement Decay-Accelerating Factor (CD55))
-
别名
- CD55
-
背景
- CD55 Molecule (Cromer blood group),CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.,DAF, CROM, CHAPLE
-
基因ID
- 1604
-
UniProt
- P08174
-
途径
- Complement System, Regulation of Leukocyte Mediated Immunity
抗原
-