CD42b 抗体
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北京 101111
Quick Overview for CD42b 抗体 (ABIN94113)
抗原
See all CD42b (GP1BA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD42b Purified
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特异性
- The antibody HIP1 reacts with an extracellular epitope of CD42b (GPIb alpha), a 135-145 kDa membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c, 160 kDa), CD42b/c forms a noncovalent complex with CD42a and CD42d.
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交叉反应 （详细）
- Human, Non-Human Primates
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Peripheral blood mononuclear cells of a patient suffering with CLL.
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亚型
- IgG1
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anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-183) antibody
GP1BA 适用: 人 WB, FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6H6H10 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-183) antibodyGP1BA 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6H6B11 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 19-291) antibodyGP1BA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 19-128) antibodyGP1BA 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 WB, FACS, ELISA, IP, ICC 宿主: 小鼠 Monoclonal AK2 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 17-282) antibodyGP1BA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 人 FACS 宿主: 小鼠 Monoclonal MM2-174 unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) antibodyGP1BA 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) (AA 1-626) antibodyGP1BA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
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别名
- CD42b
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背景
- Glycoprotein Ib platelet subunit alpha,CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.,BSS, GP1B, VWDP, CD42B, GPIbA, BDPLT1, BDPLT3, DBPLT3
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基因ID
- 2811
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UniProt
- P07359
抗原
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