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MME 抗体

This anti-MME antibody is a 小鼠 单克隆 antibody detecting MME in FACS 和 IP. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN93930
发货至: 中国

Quick Overview for MME 抗体 (ABIN93930)

抗原

See all MME 抗体
MME (Membrane Metallo-Endopeptidase (MME))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MME antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

MEM-78
  • 原理

    Anti-Hu CD10 Purified

    特异性

    The antibody MEM-78 reacts with an extracellular epitope CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    NALM-6 human pre-B cell line

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 1 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." in: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).

  • 抗原

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    CD10

    背景

    Membrane metalloendopeptidase,CD10 (neutral endopeptidase –, NEP, common acute lymphocytic leukemia antigen –, CALLA, membrane metallo-endopeptidase –, MME, enkefalinase) is a 100- kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.,CALLA, Neprilysin, Neutral endopeptidase, Enkephalinase, Atriopeptidase, MME

    基因ID

    4311

    UniProt

    P08473

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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