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BMP4 抗体

This anti-BMP4 antibody is a 小鼠 单克隆 antibody detecting BMP4 in WB, ELISA 和 Inhibition. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN934071
发货至: 中国

Quick Overview for BMP4 抗体 (ABIN934071)

抗原

See all BMP4 抗体
BMP4 (Bone Morphogenetic Protein 4 (BMP4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This BMP4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

克隆位点

M912262
  • 纯化方法

    Protein A affinity chromatography

    免疫原

    BMP4 antibody was raised in mouse using highly pure recombinant human BMP-4 as the immunogen.

    亚型

    IgG2b kappa
  • 应用备注

    ELISA: 4-8 µg/mL, Inhibition: 0.4-0.6 µg/mL, WB: 0.25-0.5 µg/mL
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • Calpe, Correia, Sancho-Serra, Krishnadath: "Comparison of newly developed anti-bone morphogenetic protein 4 llama-derived antibodies with commercially available BMP4 inhibitors." in: mAbs, Vol. 8, Issue 4, pp. 678-88, (2017) (PubMed).

  • 抗原

    BMP4 (Bone Morphogenetic Protein 4 (BMP4))

    别名

    BMP4

    背景

    Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Synonyms: Monoclonal BMP4 antibody, Anti-BMP4 antibody, BMP-4 antibody, Bone Morphogenetic antibody, 4 antibody, BMP-2B antibody, DVR4 antibody.

    分子量

    31-36 kDa (predicted detection band MW)

    途径

    Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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