BMP7 抗体
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北京 101111
Quick Overview for BMP7 抗体 (ABIN933774)
抗原
See all BMP7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein A affinity chromatography
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免疫原
- BMP7 antibody was raised in mouse using recombinant human BMP-7/OP-1 as the immunogen.
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亚型
- IgG1 kappa
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应用备注
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ELISA: 2-4 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
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别名
- BMP7
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背景
- TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures. Synonyms: Monoclonal BMP7 antibody, Anti-BMP7 antibody, BMP-7 antibody, Bone Morphogenetic antibody, 7 antibody,OP-1 antibody.
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分子量
- 28.8 kDa (predicted detection band MW)
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途径
- Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
抗原
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