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BMP7 抗体 (N-Term)

Name: BMP7 抗体 (N-Term)
SKU: ABIN2779569
Availability: OutOfStock

BMP7 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-BMP7 Antibody Titration: 1. (BMP7 抗体 (N-Term))

IHC

Host: Rabbit Target Name: BMP7 Sample Tissue: Human NCI-H226 Antibody Dilution: 1. (BMP7 抗体 (N-Term))

Host: Rabbit Target Name: BMP7 Sample Type: Human Thyroid Antibody Dilution: 1. (BMP7 抗体 (N-Term))

4 images

(8 references)

产品编号 ABIN2779569

发货至: 中国

Datasheet as PDF

抗原 See all BMP7 抗体

BMP7 (Bone Morphogenetic Protein 7 (BMP7))
抗原表位
15

11

8

7

7

5

4

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
85

43

31

18

17

4

3

2

2

2

1

1

1
人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 绵羊, 斑马鱼
宿主
79

23

3

1
兔
Compatible Secondaries
克隆类型
85

21
多克隆
标记
56

11

7

7

4

4

2

2

2

2

2

2

1

1

1

1

1
This BMP7 antibody is un-conjugated
应用范围
83

50

43

13

13

13

12

12

6

5

4

3

3

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

QGKHNSAPMF MLDLYNAMAV EEGGGPGGQG FSYPYKAVFS TQGPPLASLQ

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 91%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 82%

产品特性

This is a rabbit polyclonal antibody against BMP7. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human BMP7

Top Product

Discover our top product BMP7 Primary Antibody
anti-Bone Morphogenetic Protein 7 (BMP7) (AA 1-431) antibody
BMP7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal M1-F8 unconjugated

anti-Bone Morphogenetic Protein 7 (BMP7) (AA 132-431) antibody
BMP7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 7 (BMP7) (AA 239-431) antibody
BMP7 适用: 人, 小鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 6E5D12 unconjugated

anti-Bone Morphogenetic Protein 7 (BMP7) (N-Term) antibody
BMP7 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 7 (BMP7) (AA 293-350) antibody
BMP7 适用: 小鼠, 大鼠, 犬, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 7 (BMP7) (AA 293-431) antibody
BMP7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 7 (BMP7) (AA 280-309) antibody
BMP7 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 7 (BMP7) (AA 15-44) antibody
BMP7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 7 (BMP7) (AA 123-393) antibody
BMP7 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Bone Morphogenetic Protein 7 (BMP7) (AA 165-214) antibody
BMP7 适用: 人, 小鼠, 大鼠, 猴, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 431 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Whiteland, Spencer-Harty, Thomas, Davies, Morgan, Kynaston, Bose, Fenn, Lewis, Bodger, Jenkins, Doak: "Putative prognostic epithelial-to-mesenchymal transition biomarkers for aggressive prostate cancer." in: Experimental and molecular pathology, Vol. 95, Issue 2, pp. 220-6, (2013) (PubMed).

Lovric, Chen, Yu, Oliver, Genin, Walsh: "Effects of demineralized bone matrix on tendon-bone healing in an intra-articular rodent model." in: The American journal of sports medicine, Vol. 40, Issue 10, pp. 2365-74, (2012) (PubMed).

Rui, Lui, Rolf, Wong, Lee, Chan: "Expression of chondro-osteogenic BMPs in clinical samples of patellar tendinopathy." in: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, Vol. 20, Issue 7, pp. 1409-17, (2012) (PubMed).

Fiaschetti, Castelletti, Zoller, Schramm, Schroeder, Nagaishi, Stearns, Mittelbronn, Eggert, Westermann, Ohgaki, Shalaby, Pruschy, Arcaro, Grotzer: "Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma." in: Oncogene, Vol. 30, Issue 25, pp. 2823-35, (2011) (PubMed).

Filion, Li, Mason-Savas, Kreider, Goldstein, Ayers, Song: "Elastomeric osteoconductive synthetic scaffolds with acquired osteoinductivity expedite the repair of critical femoral defects in rats." in: Tissue engineering. Part A, Vol. 17, Issue 3-4, pp. 503-11, (2011) (PubMed).

Mae, Shirasawa, Yoshie, Sato, Kanoh, Ichikawa, Yokoyama, Yue, Tomotsune, Sasaki: "Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells." in: Biochemical and biophysical research communications, Vol. 393, Issue 4, pp. 877-82, (2010) (PubMed).

Yi, Tan, Cho, Wang, Luo, Zhang, Li, Liu: "Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17811-20, (2010) (PubMed).

Morrissey, Brown, Pitts, Vessella, Corey: "Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 2, pp. 192-205, (2010) (PubMed).
抗原

BMP7 (Bone Morphogenetic Protein 7 (BMP7))

别名

BMP7 (BMP7 产品)

别名

bmp-7 antibody, bmp7 antibody, op-1 antibody, BMP7 antibody, zgc:153025 antibody, OP-1 antibody, OP1 antibody, BMP-7 antibody, fb83f09 antibody, wu:fb83f09 antibody, bone morphogenetic protein 7 antibody, bone morphogenetic protein 7, gene 1 L homeolog antibody, bone morphogenetic protein 7b antibody, bone morphogenetic protein 7, gene 2 L homeolog antibody, bone morphogenetic protein 7a antibody, BMP7 antibody, bmp7.1.L antibody, LOC100136282 antibody, bmp7b antibody, Bmp7 antibody, LOC100008826 antibody, bmp7.2.L antibody, bmp7a antibody

背景

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
Alias Symbols: OP-1
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-7, MTUS2, TRIM27, KRTAP5-9, ACTN4, BMPR2, UBC, SMAD3, SOSTDC1, CHRDL2, GDF7, BMPR1B, NOG, ACVR2B, NCOA3, BMPR1A, ENG, ACVR2A, ACVR1, SMAD1, BMP7,
Protein Size: 431

分子量

49 kDa

基因ID

655

NCBI登录号

NM_001719, NP_001710

UniProt

P18075

途径

Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance