Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. In fact, yeast cells can proliferate normally when their CDK gene has been replaced with the homologous human gene. CDK4 deficiency has been linked to insulin deficient diabetes. Synonyms: Monoclonal Cyclin Dependent Kinase 4 antibody, Anti Cyclin Dependent Kinase 4 antibody, CDK4 antibody, PSK-J3 antibody, CMM3 antibody, Cell division kinase 4 antibody.