RUVBL1 抗体
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北京 101111
Quick Overview for RUVBL1 抗体 (ABIN932457)
抗原
See all RUVBL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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交叉反应 (详细)
- Other species not studied.
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纯化方法
- Protein G affinity chromatography
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免疫原
- RUVBL1 antibody was raised in mouse using recombinant Human Ruvb-Like 1 (E. Coli) (Ruvbl1)
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亚型
- IgG2b
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应用备注
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WB: 0.2-2 µg/mL, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- RUVBL1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))
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别名
- RUVBL1
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背景
- This gene possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. Synonyms: Monoclonal RUVBL1 antibody, Anti-RUVBL1 antibody, RuvB (E coli homolog)-like 1 antibody, RVB1 antibody, ECP54 antibody, TIP49 antibody, NMP238 antibody, TIP49A antibody.
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途径
- Telomere Maintenance
抗原
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