RUVBL1 抗体 (N-Term)
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北京 101111
Quick Overview for RUVBL1 抗体 (N-Term) (ABIN2779583)
抗原
See all RUVBL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- RUVBL1 Antibody - N-terminal region
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序列
- KIEEVKSTTK TQRIASHSHV KGLGLDESGL AKQAASGLVG QENAREACGV
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预测反应
- Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against RUVBL1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL1
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anti-RuvB-Like 1 (E. Coli) (RUVBL1) (AA 1-240) antibody
RUVBL1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RuvB-Like 1 (E. Coli) (RUVBL1) (AA 1-456) antibodyRUVBL1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3G4-1F8 unconjugated
anti-RuvB-Like 1 (E. Coli) (RUVBL1) antibodyRUVBL1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23096 unconjugated
anti-RuvB-Like 1 (E. Coli) (RUVBL1) (AA 101-400) antibodyRUVBL1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RuvB-Like 1 (E. Coli) (RUVBL1) (AA 13-23) antibodyRUVBL1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-RuvB-Like 1 (E. Coli) (RUVBL1) (AA 247-280) antibodyRUVBL1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB8415 unconjugated
anti-RuvB-Like 1 (E. Coli) (RUVBL1) antibodyRUVBL1 适用: 人 WB, FACS, ICC, DB 宿主: 小鼠 Monoclonal 2943C1a unconjugated
anti-RuvB-Like 1 (E. Coli) (RUVBL1) antibodyRUVBL1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-RuvB-Like 1 (E. Coli) (RUVBL1) antibodyRUVBL1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RuvB-Like 1 (E. Coli) (RUVBL1) antibodyKD Validated RUVBL1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2630 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111060
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))
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别名
- RUVBL1
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背景
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Background Information: RUVBL1 possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. It is the component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex.
Gene Name: RuvB-like 1 (E. coli)
Alternative Symbols: RVB1, TIH1, ECP54, TIP49, ECP-54, INO80H, NMP238, PONTIN, TIP49A, NMP 238, Pontin52
Protein Name: RuvB-like 1
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分子量
- 50kDa
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基因ID
- 8607
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NCBI登录号
- NP_003698
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UniProt
- Q9Y265
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途径
- Telomere Maintenance
抗原
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