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MSH6 抗体

The 小鼠 单克隆 anti-MSH6 antibody (Clone 3A10H7) (ABIN931485) specifically detects MSH6 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN931485
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for MSH6 抗体 (ABIN931485)

抗原

See all MSH6 抗体
MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

适用

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宿主

  • 119
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小鼠

克隆类型

  • 156
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  • 1
单克隆

标记

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This MSH6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

3A10H7
  • 免疫原

    MSH6 antibody was raised in Mouse using a purified recombinant fragment of MSH6 expressed in E. coli as the immunogen.

    亚型

    IgG1
  • 应用备注

    ELISA: 1:10,000, WB: 1:500-1:2000
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term storage. Store at -20 °C for long term storage.
  • 抗原

    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

    别名

    MSH6

    背景

    Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair. Synonyms: Monoclonal MSH6 antibody, Anti-MSH6 antibody, Muts Homolog 6 antibody, GTBP antibody, HNPCC5 antibody, HSAP antibody.

    途径

    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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