MLL/KMT2A 抗体 (AA 3751-3968)
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北京 101111
Quick Overview for MLL/KMT2A 抗体 (AA 3751-3968) (ABIN931441)
抗原
See all MLL/KMT2A (MLL) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 3751-3968
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免疫原
- MLL antibody was raised in Mouse using a purified recombinant fragment of MLL(aa3751-3968) expressed in E. coli as the immunogen.
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亚型
- IgG1
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应用备注
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ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
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- MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
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别名
- MLL
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背景
- MLL contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Synonyms: Monoclonal MLL antibody, Anti-MLL antibody, Myeloid/lymphoid leukemia antibody, ALL-1 antibody, ALL 1 antibody, HRX antibody, Lysine N-methyltransferase 2A antibody, Trithorax-like protein antibody, Zinc finger protein HRX antibody.
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途径
- Warburg Effect
抗原
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