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Androgen Receptor 抗体 (AA 689-919)

This anti-Androgen Receptor antibody is a 小鼠 单克隆 antibody detecting Androgen Receptor in WB 和 ELISA. Suitable for 人.
产品编号 ABIN931406
发货至: 中国

Quick Overview for Androgen Receptor 抗体 (AA 689-919) (ABIN931406)

抗原

See all Androgen Receptor (AR) 抗体
Androgen Receptor (AR)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Androgen Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1A9D12
  • 抗原表位

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    AA 689-919

    免疫原

    AR antibody was raised in Mouse using a purified recombinant fragment of AR(aa689-919) expressed in E. coli as the immunogen.

    亚型

    IgG1
  • 应用备注

    ELISA: 1:10,000, WB: 1:500-1:2000
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term storage. Store at -20 °C for long term storage.
  • 抗原

    Androgen Receptor (AR)

    别名

    AR

    背景

    AR functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. Synonyms: Monoclonal AR antibody, Anti-AR antibody, Androgen Receptor antibody.

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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