ABL1 抗体 (AA 577-650)
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北京 101111
Quick Overview for ABL1 抗体 (AA 577-650) (ABIN931298)
抗原
See all ABL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 577-650
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免疫原
- ABL1 antibody was raised in Mouse using a purified recombinant fragment of ABL1(aa577-650) expressed in E. coli as the immunogen.
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亚型
- IgG1
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应用备注
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ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
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- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
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别名
- ABL1
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背景
- The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of ABL1 protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9,22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes, leading to a fusion gene present in many cases of chronic myelogenous leukemia. Synonyms: Monoclonal ABL1 antibody, Anti-ABL1 antibody, V-abl Abelson murine leukemia viral oncogene homolog 1 antibody.
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途径
- Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
抗原
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