CBFB 抗体
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北京 101111
Quick Overview for CBFB 抗体 (ABIN931127)
抗原
See all CBFB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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交叉反应 (详细)
- Other species not studied.
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纯化方法
- Protein G affinity chromatography
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免疫原
- CBFB antibody was raised in mouse using recombinant Human Core-Binding Factor, Beta Subunit
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亚型
- IgG1
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应用备注
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WB: 0.2-2 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- CBFB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- CBFB (Core-Binding Factor, beta Subunit (CBFB))
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别名
- CBFB
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背景
- The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Synonyms: Monoclonal CBFB antibody, Anti-CBFB antibody, Core-binding factor subunit beta antibody, PEBP2B antibody.
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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