CBFB 抗体 (N-Term)
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- 抗原 See all CBFB 抗体
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBFB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- CBF beta Antibody detects endogenous levels of total CBF beta.
- 预测反应
- Pig,Bovine,Horse,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CBF beta, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CBFB Primary Antibody
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anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-187) antibody
CBFB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-182) antibodyCBFB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 61-90) antibodyCBFB 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21198 unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-182) antibodyCBFB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) antibodyCBFB 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (Center) antibodyCBFB 适用: 人 ELISA, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 1-182) antibodyCBFB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (AA 74-163) antibodyCBFB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) (N-Term) antibodyCBFB 适用: 人, 斑马鱼, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Core-Binding Factor, beta Subunit (CBFB) antibodyCBFB 适用: 人, 小鼠 WB, IHC, IF/ICC, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
- 别名
- CBFB (CBFB 产品)
- 别名
- PEBP2B antibody, Cbfb antibody, pebp2b antibody, Pebp2 antibody, CBFB antibody, unp1266 antibody, cbf-beta antibody, cbfbeta antibody, pea2-beta antibody, pebp2-beta antibody, AI893578 antibody, PEA2 antibody, PEBP2b antibody, Pebpb2 antibody, core-binding factor beta subunit antibody, core binding factor beta subunit antibody, core-binding factor, beta subunit antibody, core-binding factor, beta subunit S homeolog antibody, core binding factor beta antibody, CBFB antibody, Cbfb antibody, cbfb antibody, cbfb.S antibody
- 背景
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Description: Forms the heterodimeric complex core-binding factor (CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3). RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBF complexes repress ZBTB7B transcription factor during cytotoxic (CD8+) T cell development. They bind to RUNX-binding sequence within the ZBTB7B locus acting as transcriptional silencer and allowing for cytotoxic T cell differentiation.
Gene: CBFB
- 分子量
- 22 kDa
- 基因ID
- 865
- UniProt
- Q13951
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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