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Fibrillarin 抗体

This anti-Fibrillarin antibody is a 小鼠 单克隆 antibody detecting Fibrillarin in DB. Suitable for 人.
产品编号 ABIN931035
发货至: 中国

Quick Overview for Fibrillarin 抗体 (ABIN931035)

抗原

See all Fibrillarin (FBL) 抗体
Fibrillarin (FBL)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Fibrillarin antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

2350C1
  • 交叉反应

    交叉反应 (详细)

    Other species not studied.

    纯化方法

    Protein G affinity chromatography

    免疫原

    FBL antibody was raised in mouse using recombinant Human Fibrillarin

    亚型

    IgG1
  • 应用备注

    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    FBL antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原

    Fibrillarin (FBL)

    别名

    FBL

    背景

    This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. Synonyms: Monoclonal FBL antibody, Anti-FBL antibody, Fibrillarin antibody, FIB antibody, FLRN antibody, RNU3IP1 antibody.

    途径

    Ribonucleoside Biosynthetic Process
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