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E2F6 抗体

This anti-E2F6 antibody is a 小鼠 单克隆 antibody detecting E2F6 in ICC 和 DB. Suitable for 人.
产品编号 ABIN930975
发货至: 中国

Quick Overview for E2F6 抗体 (ABIN930975)

抗原

See all E2F6 抗体
E2F6 (E2F Transcription Factor 6 (E2F6))

适用

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宿主

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  • 6
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小鼠

克隆类型

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  • 8
单克隆

标记

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This E2F6 antibody is un-conjugated

应用范围

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Immunocytochemistry (ICC), Dot Blot (DB)

克隆位点

E2F6B9E2
  • 交叉反应

    交叉反应 (详细)

    Other species not studied.

    纯化方法

    Protein G affinity chromatography

    免疫原

    E2 F6 antibody was raised in mouse using recombinant Human E2 Transcription Factor 6, Transcript Variant A

    亚型

    IgG1
  • 应用备注

    ICC: 2-100 µg/mL
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    E2 F6 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
  • 抗原

    E2F6 (E2F Transcription Factor 6 (E2F6))

    别名

    E2F6

    背景

    This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Synonyms: Monoclonal E2F6 antibody, Anti-E2F6 antibody, E2F transcription factor 6 antibody, E2F-6 antibody.
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