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PROX1 抗体 (C-Term)

Cited in 3+ publications. This anti-PROX1 antibody is a 兔 多克隆 antibody detecting PROX1 in WB, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN929458
发货至: 中国
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Quick Overview for PROX1 抗体 (C-Term) (ABIN929458)

抗原

See all PROX1 抗体
PROX1 (Prospero Homeobox 1 (PROX1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PROX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    C-Term

    特异性

    This antibody will detect Prox-1 in the nucleus of lymphatic endothelial cells by immunostaining, and human Prox 1 by western blot.

    交叉反应

    人, 小鼠, 大鼠

    交叉反应 (详细)

    Equal reactivity with Human, Mouse, and Rat

    纯化方法

    Protein A affinity chromatography

    免疫原

    Prox 1 antibody was raised in rabbit using recombinant human C-terminal part of Prox-1 (homeo domain and prospero domain) as the immunogen

    亚型

    IgG
  • 应用备注

    WB: 1-5µg/mL. For other applications, optimal conditions should be determined by end-user
    Optimal conditions should be determined by the investigator.

    说明

    The lyophilized IgG is stable at 4 °C for at least one month and for more than a year when kept at -20 °C. When reconstituted in sterile water to a concentration of >0.5 mg/mL the antibody is stable for at least six weeks at 2-4 °C in the presence of a preservative.

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    IgG fraction supplied lyophilizedfrom PBS, pH 7.4 with no preservative.

    储存液

    Without preservative

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store lyophilized antibody at -20 °C. Following reconstitution store at 4 °C in the short-term. For longer term storage aliquot and store at -20 °C or -70 °C.
  • Zhang, Brady, Liang, Wu, Henkemeyer, Yan: "EphB4 forward signalling regulates lymphatic valve development." in: Nature communications, Vol. 6, pp. 6625, (2016) (PubMed).

    Kulkarni, Herman, Ikegami, Greenberg, Akeson: "Lymphatic ontogeny and effect of hypoplasia in developing lung." in: Mechanisms of development, Vol. 128, Issue 1-2, pp. 29-40, (2011) (PubMed).

    Kulkarni, Greenberg, Akeson: "NFATc1 regulates lymphatic endothelial development." in: Mechanisms of development, Vol. 126, Issue 5-6, pp. 350-65, (2009) (PubMed).

  • 抗原

    PROX1 (Prospero Homeobox 1 (PROX1))

    别名

    Prox 1

    背景

    Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox-1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. Synonyms: Polyclonal Prox 1 antibody, Anti-Prox 1 antibody, Prox-1 antibody, Prospero related homeobox 1 antibody, Homeobox prospero like protein antibody, Homeobox prospero like protein PROX1 antibody, Prospero homeobox protein 1 antibody, Prospero related homeobox 1 antibody.

    途径

    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
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