PROX1 抗体 (C-Term)
Quick Overview for PROX1 抗体 (C-Term) (ABIN929458)
抗原
See all PROX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody will detect Prox-1 in the nucleus of lymphatic endothelial cells by immunostaining, and human Prox 1 by western blot.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 (详细)
- Equal reactivity with Human, Mouse, and Rat
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纯化方法
- Protein A affinity chromatography
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免疫原
- Prox 1 antibody was raised in rabbit using recombinant human C-terminal part of Prox-1 (homeo domain and prospero domain) as the immunogen
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亚型
- IgG
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应用备注
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WB: 1-5µg/mL. For other applications, optimal conditions should be determined by end-user
Optimal conditions should be determined by the investigator. -
说明
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The lyophilized IgG is stable at 4 °C for at least one month and for more than a year when kept at -20 °C. When reconstituted in sterile water to a concentration of >0.5 mg/mL the antibody is stable for at least six weeks at 2-4 °C in the presence of a preservative.
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- IgG fraction supplied lyophilizedfrom PBS, pH 7.4 with no preservative.
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储存液
- Without preservative
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized antibody at -20 °C. Following reconstitution store at 4 °C in the short-term. For longer term storage aliquot and store at -20 °C or -70 °C.
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: "EphB4 forward signalling regulates lymphatic valve development." in: Nature communications, Vol. 6, pp. 6625, (2016) (PubMed).
: "Lymphatic ontogeny and effect of hypoplasia in developing lung." in: Mechanisms of development, Vol. 128, Issue 1-2, pp. 29-40, (2011) (PubMed).
: "NFATc1 regulates lymphatic endothelial development." in: Mechanisms of development, Vol. 126, Issue 5-6, pp. 350-65, (2009) (PubMed).
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: "EphB4 forward signalling regulates lymphatic valve development." in: Nature communications, Vol. 6, pp. 6625, (2016) (PubMed).
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- PROX1 (Prospero Homeobox 1 (PROX1))
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别名
- Prox 1
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背景
- Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox-1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. Synonyms: Polyclonal Prox 1 antibody, Anti-Prox 1 antibody, Prox-1 antibody, Prospero related homeobox 1 antibody, Homeobox prospero like protein antibody, Homeobox prospero like protein PROX1 antibody, Prospero homeobox protein 1 antibody, Prospero related homeobox 1 antibody.
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途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
抗原
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