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PROX1 抗体 (AA 492-522)

PROX1 适用: 人, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3032348
发货至: 中国
  • 抗原 See all PROX1 抗体
    PROX1 (Prospero Homeobox 1 (PROX1))
    抗原表位
    • 16
    • 14
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 492-522
    适用
    • 92
    • 48
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 84
    • 8
    克隆类型
    • 82
    • 10
    多克隆
    标记
    • 47
    • 8
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PROX1 antibody is un-conjugated
    应用范围
    • 82
    • 47
    • 37
    • 28
    • 13
    • 11
    • 9
    • 4
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    交叉反应 (详细)
    Expected species reactivity: Mouse
    纯化方法
    Purified
    免疫原
    A portion of amino acids 492-522 from the human protein was used as the immunogen for this PROX1 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PROX1 Primary Antibody
  • 应用备注
    Titration of the PROX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,Immunofluorescence: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the PROX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    PROX1 (Prospero Homeobox 1 (PROX1))
    别名
    PROX1 (PROX1 产品)
    别名
    xprox1 antibody, prospero antibody, PROX1 antibody, LOC100232600 antibody, A230003G05Rik antibody, prox1 antibody, zgc:111888 antibody, prospero homeobox 1 antibody, prospero homeobox 1 L homeolog antibody, prospero homeobox 1a antibody, PROX1 antibody, prox1.L antibody, prox1 antibody, Prox1 antibody, prox1a antibody
    背景
    The expression pattern of Prox1 suggests that it has a role in a variety of embryonic tissues, including lens. Prox mRNA is present in many different human tissues with lens demonstrating the highest level. Homozygous Prox1-null mice die at midgestation from multiple developmental defects, and a targeted effect on lens development has been reported. Prox1 inactivation caused abnormal cellular proliferation, downregulated expression of the cell cycle inhibitors Cdkn1b and Cdkn1c, misexpression of E-cadherin, and excessive apoptosis. Consequently, mutant lens cells failed to polarize and elongate properly, resulting in a hollow lens.
    UniProt
    Q92786
    途径
    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
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