CMA1 抗体 (C-Term)
Quick Overview for CMA1 抗体 (C-Term) (ABIN929416)
抗原
See all CMA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- CMA1 antibody was raised in rabbit using the C terminal of CMA1 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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CMA1 Blocking Peptide, (ABIN938181), is also available for use as a blocking control in assays to test for specificity of this CMA1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- CMA1 (Chymase 1, Mast Cell (CMA1))
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别名
- CMA1
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背景
- CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. Synonyms: Polyclonal CMA1 antibody, Anti-CMA1 antibody, chymase 1, mast cell antibody, CYH antibody, MCT1 antibody, MGC119890 antibody, MGC119891 antibody, chymase antibody.
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
抗原
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