AP2A2 抗体 (C-Term)
Quick Overview for AP2A2 抗体 (C-Term) (ABIN929411)
抗原
See all AP2A2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- AP2 A2 antibody was raised in rabbit using the C terminal of AP2 2 as the immunogen
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anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 590-939) antibody
AP2A2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 590-939) antibodyAP2A2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 21-150) antibodyAP2A2 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (Internal Region) antibodyAP2A2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 610-637) antibodyAP2A2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22030 unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) antibodyAP2A2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 612-661) antibodyAP2A2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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AP2A2 Blocking Peptide, (ABIN5612096), is also available for use as a blocking control in assays to test for specificity of this AP2A2 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- AP2A2 (Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2))
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别名
- AP2A2
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背景
- AP2A2 is a component of the adaptor protein complex 2 (AP-2). AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif. Synonyms: Polyclonal AP2A2 antibody, Anti-AP2A2 antibody, adaptor-related protein complex 2, alpha 2 subunit antibody, ADTAB antibody, CLAPA2 antibody, HIP9 antibody, HYPJ antibody.
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome
抗原
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