NCF4 抗体 (C-Term)
Quick Overview for NCF4 抗体 (C-Term) (ABIN929086)
抗原
See all NCF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- NCF4 antibody was raised in rabbit using the C terminal of NCF4 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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NCF4 Blocking Peptide, (ABIN5614928), is also available for use as a blocking control in assays to test for specificity of this NCF4 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
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别名
- NCF4
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背景
- NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. Synonyms: Polyclonal NCF4 antibody, Anti-NCF4 antibody, neutrophil cytosolic factor 4, 40kDa antibody, MGC3810 antibody, NCF antibody, P40PHOX antibody, SH3PXD4 antibody.
抗原
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