Glutaredoxin 2 抗体 (Middle Region)
Quick Overview for Glutaredoxin 2 抗体 (Middle Region) (ABIN929001)
抗原
See all Glutaredoxin 2 (GRX2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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纯化方法
- Purified
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免疫原
- GLRX2 antibody was raised in rabbit using the middle region of GLRX2 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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GLRX2 Blocking Peptide, (ABIN5613785), is also available for use as a blocking control in assays to test for specificity of this GLRX2 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Glutaredoxin 2 (GRX2)
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别名
- GLRX2
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背景
- GLRX2 is a glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress.GLRX2 is involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress.GLRX2 acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides.GLRX2 can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions.GLRX2 efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Synonyms: Polyclonal GLRX2 antibody, Anti-GLRX2 antibody, glutaredoxin 2 antibody, GRX2 antibody, bA101E13.1 antibody.
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途径
- Cell RedoxHomeostasis
抗原
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