WB: 0.2-1 µg/mL Optimal conditions should be determined by the investigator.
限制
仅限研究用
状态
Lyophilized
浓度
Lot specific
缓冲液
Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
抗原
RENT2/UPF2 (UPF2)
(UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
别名
UPF2
背景
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein. Synonyms: Polyclonal UPF2 antibody, Anti-UPF2 antibody, UPF2 regulator of nonsense transcripts homolog, yeast antibody, DKFZp434D222 antibody, HUPF2 antibody, KIAA1408 antibody, MGC138834 antibody, MGC138835 antibody, RENT2 antibody, smg-3 antibody.