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FGD1 抗体 (N-Term)

This anti-FGD1 antibody is a 兔 多克隆 antibody detecting FGD1 in WB. Suitable for 人, Cow 和 犬.
产品编号 ABIN927716
发货至: 中国

Quick Overview for FGD1 抗体 (N-Term) (ABIN927716)

抗原

See all FGD1 抗体
FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

适用

  • 9
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
人, Cow, 犬

宿主

  • 9

克隆类型

  • 9
多克隆

标记

  • 9
This FGD1 antibody is un-conjugated

应用范围

  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 4
    • 2
    • 1
    • 1
    N-Term

    交叉反应

    牛, 犬

    纯化方法

    Purified

    免疫原

    FGD1 antibody was raised in rabbit using the N terminal of FGD1 as the immunogen
  • 应用备注

    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    FGD1 Blocking Peptide, (ABIN939123), is also available for use as a blocking control in assays to test for specificity of this FGD1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

    别名

    FGD1

    背景

    FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. Synonyms: Polyclonal FGD1 antibody, Anti-FGD1 antibody, FYVE, RhoGEF and PH domain containing 1, faciogenital dysplasia antibody, AAS antibody, FGDY antibody, ZFYVE3 antibody.

    途径

    Neurotrophin Signaling Pathway
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