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MDC1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects MDC1 in WB. It exhibits reactivity toward 人.
产品编号 ABIN927646
发货至: 中国
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Quick Overview for MDC1 抗体 (C-Term) (ABIN927646)

抗原

See all MDC1 抗体
MDC1 (Mdc1 (MDC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This MDC1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    纯化方法

    Purified

    免疫原

    MDC1 antibody was raised in rabbit using the C terminal of MDC1 as the immunogen
  • 应用备注

    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    MDC1 (Mdc1 (MDC1))

    别名

    MDC1

    背景

    The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. Synonyms: Polyclonal MDC1 antibody, Anti-MDC1 antibody, mediator of DNA-damage checkpoint 1 antibody, DKFZp781A0122 antibody, KIAA0170 antibody, MGC166888 antibody, NFBD1 antibody.
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