MDC1 抗体 (C-Term)
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Quick Overview for MDC1 抗体 (C-Term) (ABIN927646)
抗原
See all MDC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- MDC1 antibody was raised in rabbit using the C terminal of MDC1 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- MDC1 (Mdc1 (MDC1))
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别名
- MDC1
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背景
- The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. Synonyms: Polyclonal MDC1 antibody, Anti-MDC1 antibody, mediator of DNA-damage checkpoint 1 antibody, DKFZp781A0122 antibody, KIAA0170 antibody, MGC166888 antibody, NFBD1 antibody.
抗原
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