CCR5 抗体 (Middle Region)
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北京 101111
Quick Overview for CCR5 抗体 (Middle Region) (ABIN927305)
抗原
See all CCR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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交叉反应
- 小鼠
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纯化方法
- Purified
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免疫原
- CCR5 antibody was raised in rabbit using the middle region of CCR5 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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CCR5 Blocking Peptide, (ABIN5612739), is also available for use as a blocking control in assays to test for specificity of this CCR5 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
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别名
- CCR5
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背景
- CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this protein was also detected in a promyeloblastic cell line, suggesting that CCR5 may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Synonyms: Polyclonal CCR5 antibody, Anti-CCR5 antibody, chemokine, C-C motif receptor 5 antibody, CC-CKR-5 antibody, CCCKR5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody.
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
抗原
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