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CCR5 抗体 (Middle Region)

The 兔 多克隆 anti-CCR5 antibody is suitable to detect CCR5 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN927305
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCR5 抗体 (Middle Region) (ABIN927305)

抗原

See all CCR5 抗体
CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

  • 173
  • 49
  • 41
  • 11
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人, 小鼠

宿主

  • 112
  • 45
  • 14
  • 12
  • 1
  • 1

克隆类型

  • 109
  • 67
  • 5
多克隆

标记

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This CCR5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    交叉反应

    小鼠

    纯化方法

    Purified

    免疫原

    CCR5 antibody was raised in rabbit using the middle region of CCR5 as the immunogen
  • 应用备注

    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    CCR5 Blocking Peptide, (ABIN5612739), is also available for use as a blocking control in assays to test for specificity of this CCR5 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

    别名

    CCR5

    背景

    CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this protein was also detected in a promyeloblastic cell line, suggesting that CCR5 may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Synonyms: Polyclonal CCR5 antibody, Anti-CCR5 antibody, chemokine, C-C motif receptor 5 antibody, CC-CKR-5 antibody, CCCKR5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody.

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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