IDE 抗体 (N-Term)
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Quick Overview for IDE 抗体 (N-Term) (ABIN927297)
抗原
See all IDE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Purified
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免疫原
- IDE antibody was raised in rabbit using the N terminal of IDE as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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IDE Blocking Peptide, (ABIN936344), is also available for use as a blocking control in assays to test for specificity of this IDE antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- IDE (Insulin-Degrading Enzyme (IDE))
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别名
- IDE
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背景
- This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Synonyms: Polyclonal IDE antibody, Anti-IDE antibody, insulin-degrading enzyme antibody, FLJ35968 antibody, INSULYSIN antibody.
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途径
- SARS-CoV-2 Protein Interactome
抗原
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