WB: 0.2-1 µg/mL Optimal conditions should be determined by the investigator.
限制
仅限研究用
状态
Lyophilized
浓度
Lot specific
缓冲液
Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
抗原
TYK2
(Tyrosine Kinase 2 (TYK2))
别名
TYK2
背景
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. Synonyms: Polyclonal TYK2 antibody, Anti-TYK2 antibody, tyrosine kinase 2 antibody, JTK1 antibody.