(1 reference)-
- 抗原
- Prothrombin Fragment 2
- 适用
- 人
- 宿主
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绵羊
- 克隆类型
- 多克隆
- 纯化方法
- Affinity chromatography purified
- 免疫原
- Prothrombin fragment 2 antibody was raised in sheep using human Prothrombin purified from plasma as the immunogen.
- 亚型
- IgG
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- 应用备注
- Optimal conditions should be determined byt he investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Supplied in liquid form with 10 mM HEPES, pH 7.4, 150 mM NaCl, 50 % (v/v) glycerol.
- 注意事项
-
Avoid repeated freeze/thaw cycles.
Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use. - 储存条件
- -20 °C
- 储存方法
- Store at -10 to -20 °C.
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: "Induction of microglial toll-like receptor 4 by prothrombin kringle-2: a potential pathogenic mechanism in Parkinson's disease." in: Scientific reports, Vol. 5, pp. 14764, (2016) (PubMed).
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: "Induction of microglial toll-like receptor 4 by prothrombin kringle-2: a potential pathogenic mechanism in Parkinson's disease." in: Scientific reports, Vol. 5, pp. 14764, (2016) (PubMed).
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- 抗原
- Prothrombin Fragment 2
- 背景
- Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to gamma-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Synonyms: Polyclonal Prothrombin fragment 2 antibody, Anti-Prothrombin fragment 2 antibody.
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