Prothrombin Fragment 2 (C-Term) 抗体
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北京 101111
Quick Overview for Prothrombin Fragment 2 (C-Term) 抗体 (ABIN3042926)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Prothrombin/F2 Antibody
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序列
- THVFRLKRWM QKV
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Prothrombin/F2 Antibody. Tested in WB applications. This antibody reacts with Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of rat Prothrombin.
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亚型
- IgG
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anti-Prothrombin Fragment 2 (AA 97-124) antibody
适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 4G13G9 unconjugated
anti-Prothrombin Fragment 2 (AA 97-124) antibody适用: 人, 大鼠, 小鼠 WB 宿主: 小鼠 Monoclonal 5B6G1 unconjugated
anti-Prothrombin Fragment 2 antibody适用: 人 WB, IP 宿主: 兔 Monoclonal ACBD-6 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Heparin impairs angiogenesis through inhibition of microRNA-10b." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26616-27, (2011) (PubMed).
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- Prothrombin Fragment 2
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背景
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Background: F2 (Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. Royle et al. (1987) assigned the gene for human prothrombin (F2) to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII (F8), and XIII (F13A1). Thrombin also inhibits coagulation by activating protein C.
Gene Full Name: coagulation factor II(thrombin)
Sequence Similarities: Belongs to the peptidase S1 family.
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分子量
- 100 kDa
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基因ID
- 29251
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UniProt
- P18292
抗原
-
