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Cyclin D1 抗体 (Middle Region)

CCND1 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 犬, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN926904
发货至: 中国
  • 抗原 See all Cyclin D1 (CCND1) 抗体
    Cyclin D1 (CCND1)
    抗原表位
    • 22
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    Middle Region
    适用
    • 236
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    人, 小鼠, 大鼠, Cow, 小鸡, 犬, 斑马鱼, 非洲爪蟾
    宿主
    • 204
    • 56
    • 1
    克隆类型
    • 193
    • 66
    多克隆
    标记
    • 117
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    This Cyclin D1 antibody is un-conjugated
    应用范围
    • 197
    • 89
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    Western Blotting (WB)
    交叉反应
    小鼠, 大鼠, 犬, 牛, 斑马鱼, Frog, 小鸡
    纯化方法
    Purified
    免疫原
    CCND1 antibody was raised in rabbit using the middle region of CCND1 as the immunogen
    Top Product
    Discover our top product CCND1 Primary Antibody
  • 应用备注
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    CCND1 Blocking Peptide, catalog no. 33R-1076, is also available for use as a blocking control in assays to test for specificity of this CCND1 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    Cyclin D1 (CCND1)
    别名
    CCND1 (CCND1 产品)
    别名
    BCL1 antibody, D11S287E antibody, PRAD1 antibody, U21B31 antibody, AI327039 antibody, CycD1 antibody, Cyl-1 antibody, bcl-1 antibody, cD1 antibody, cb161 antibody, cycd1 antibody, etID37810.7 antibody, fb52e01 antibody, fc45c08 antibody, fc83a12 antibody, id:ibd1198 antibody, wu:fb52e01 antibody, wu:fc45c08 antibody, wu:fc83a12 antibody, ccnd1b antibody, prad1 antibody, ccnd1 antibody, ccnd1a antibody, bcl1 antibody, d11s287e antibody, u21b31 antibody, CCND1 antibody, cyclin D1 antibody, cyclin D1 S homeolog antibody, cyclin D1 L homeolog antibody, CCND1 antibody, Ccnd1 antibody, ccnd1 antibody, ccnd1.S antibody, ccnd1.L antibody
    背景
    CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. Synonyms: Polyclonal CCND1 antibody, Anti-CCND1 antibody, cyclin D1 antibody, BCL1 antibody, D11S287E antibody, PRAD1 antibody, U21B31 antibody.
    途径
    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
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