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Cullin 2 抗体 (Middle Region)

CUL2 适用: 人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN926903
发货至: 中国
  • 抗原 See all Cullin 2 (CUL2) 抗体
    Cullin 2 (CUL2)
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 73
    • 38
    • 24
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾
    宿主
    • 70
    • 2
    • 1
    克隆类型
    • 64
    • 9
    多克隆
    标记
    • 31
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cullin 2 antibody is un-conjugated
    应用范围
    • 37
    • 30
    • 14
    • 13
    • 12
    • 11
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠, 大鼠, 犬, 牛, Frog
    纯化方法
    Purified
    免疫原
    CUL2 antibody was raised in rabbit using the middle region of CUL2 as the immunogen
    Top Product
    Discover our top product CUL2 Primary Antibody
  • 应用备注
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    CUL2 Blocking Peptide, catalog no. 33R-3799, is also available for use as a blocking control in assays to test for specificity of this CUL2 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    Cullin 2 (CUL2)
    别名
    CUL2 (CUL2 产品)
    别名
    cul2 antibody, Cullin-2 antibody, fj48a06 antibody, wu:fj48a06 antibody, cullin-2 antibody, LOC100221330 antibody, 1300003D18Rik antibody, 4932411N15Rik antibody, AI327301 antibody, mKIAA4106 antibody, ATCUL2 antibody, F22D16.2 antibody, F22D16_2 antibody, cullin 2 antibody, cullin 2 antibody, cullin-2 antibody, putative cullin-2 (cul-2) antibody, cullin 2 L homeolog antibody, Cullin-2 antibody, cul2 antibody, CUL2 antibody, PTRG_05231 antibody, Smp_079740 antibody, LOC100550749 antibody, Cul2 antibody, cul2.L antibody, cul-2 antibody
    背景
    CUL2 is a core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. This protein may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 By similarity. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF). Synonyms: Polyclonal CUL2 antibody, Anti-CUL2 antibody, cullin 2 antibody, MGC131970 antibody.
    途径
    M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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