Cullin 2 抗体 (Middle Region)
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- 抗原 See all Cullin 2 (CUL2) 抗体
- Cullin 2 (CUL2)
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cullin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠, 大鼠, 犬, 牛, Frog
- 纯化方法
- Purified
- 免疫原
- CUL2 antibody was raised in rabbit using the middle region of CUL2 as the immunogen
- Top Product
- Discover our top product CUL2 Primary Antibody
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- 应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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CUL2 Blocking Peptide, catalog no. 33R-3799, is also available for use as a blocking control in assays to test for specificity of this CUL2 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- Cullin 2 (CUL2)
- 别名
- CUL2 (CUL2 产品)
- 别名
- cul2 antibody, Cullin-2 antibody, fj48a06 antibody, wu:fj48a06 antibody, cullin-2 antibody, LOC100221330 antibody, 1300003D18Rik antibody, 4932411N15Rik antibody, AI327301 antibody, mKIAA4106 antibody, ATCUL2 antibody, F22D16.2 antibody, F22D16_2 antibody, cullin 2 antibody, cullin 2 antibody, cullin-2 antibody, putative cullin-2 (cul-2) antibody, cullin 2 L homeolog antibody, Cullin-2 antibody, cul2 antibody, CUL2 antibody, PTRG_05231 antibody, Smp_079740 antibody, LOC100550749 antibody, Cul2 antibody, cul2.L antibody, cul-2 antibody
- 背景
- CUL2 is a core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. This protein may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 By similarity. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF). Synonyms: Polyclonal CUL2 antibody, Anti-CUL2 antibody, cullin 2 antibody, MGC131970 antibody.
- 途径
- M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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