Cullin 2 抗体 (Middle Region)
Quick Overview for Cullin 2 抗体 (Middle Region) (ABIN926903)
抗原
See all Cullin 2 (CUL2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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交叉反应
- 小鼠, 大鼠, 犬, 牛, Frog
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纯化方法
- Purified
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免疫原
- CUL2 antibody was raised in rabbit using the middle region of CUL2 as the immunogen
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anti-Cullin 2 (CUL2) (C-Term) antibody
CUL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 591-742) antibodyCUL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyVerified CUL2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cullin 2 (CUL2) antibodyCUL2 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Cullin 2 (CUL2) (AA 40-310) antibodyCUL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 264-280), (Middle Region) antibodyCUL2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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CUL2 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CUL2 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Cullin 2 (CUL2)
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别名
- CUL2
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背景
- CUL2 is a core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. This protein may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 By similarity. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF). Synonyms: Polyclonal CUL2 antibody, Anti-CUL2 antibody, cullin 2 antibody, MGC131970 antibody.
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途径
- M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
抗原
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