AIF 抗体 (Middle Region)
Quick Overview for AIF 抗体 (Middle Region) (ABIN926871)
抗原
See all AIF (AIFM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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交叉反应
- 小鼠, 大鼠, 犬, 牛, 斑马鱼, 小鸡
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纯化方法
- Purified
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免疫原
- AIFM1 antibody was raised in rabbit using the middle region of AIFM1 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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AIFM1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this AIFM1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
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别名
- AIFM1
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背景
- AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene. Synonyms: Polyclonal AIFM1 antibody, Anti-AIFM1 antibody, apoptosis-inducing factor, mitochondrion-associated, 1 antibody, AIF antibody, MGC111425 antibody, PDCD8 antibody.
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
抗原
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