Exportin 2 抗体 (N-Term)
Quick Overview for Exportin 2 抗体 (N-Term) (ABIN926854)
抗原
See all Exportin 2 (CSE1L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 小鼠, 大鼠, 斑马鱼, 牛, Frog, 小鸡
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纯化方法
- Purified
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免疫原
- CSE1 L antibody was raised in rabbit using the N terminal of CSE1 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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CSE1L Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CSE1L antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
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别名
- CSE1L
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背景
- Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the protein may play a role both in apoptosis and in cell proliferation. Synonyms: Polyclonal CSE1L antibody, Anti-CSE1L antibody, CSE1 chromosome segregation 1-like, yeast antibody, CAS antibody, CSE1 antibody, MGC117283 antibody, MGC130036 antibody, MGC130037 antibody, XPO2 antibody.
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途径
- Protein targeting to Nucleus
抗原
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