OGG1 抗体 (C-Term)
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Quick Overview for OGG1 抗体 (C-Term) (ABIN926698)
抗原
See all OGG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- OGG1 antibody was raised in rabbit using the C terminal of OGG1 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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OGG1 Blocking Peptide, (ABIN936997), is also available for use as a blocking control in assays to test for specificity of this OGG1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
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别名
- OGG1
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背景
- This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Synonyms: Polyclonal OGG1 antibody, Anti-OGG1 antibody, 8-oxoguanine DNA glycosylase antibody, HMMH antibody, HOGG1 antibody, MUTM antibody, OGH1 antibody.
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途径
- DNA Damage Repair
抗原
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