Hexokinase 1 抗体 (N-Term)
Quick Overview for Hexokinase 1 抗体 (N-Term) (ABIN926654)
抗原
See all Hexokinase 1 (HK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Purified
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免疫原
- HK1 antibody was raised in rabbit using the N terminal of HK1 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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HK1 Blocking Peptide, (ABIN937173), is also available for use as a blocking control in assays to test for specificity of this HK1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Hexokinase 1 (HK1)
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别名
- HK1
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背景
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. Synonyms: Polyclonal HK1 antibody, Anti-HK1 antibody, hexokinase 1 antibody, HK1-ta antibody, HK1-tb antibody, HK1-tc antibody, HKI antibody, HXK1 antibody.
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途径
- Carbohydrate Homeostasis, Warburg Effect
抗原
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