DDB2 抗体 (C-Term)
Quick Overview for DDB2 抗体 (C-Term) (ABIN926426)
抗原
See all DDB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- DDB2 antibody was raised in rabbit using the C terminal of DDB2 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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DDB2 Blocking Peptide, (ABIN939596), is also available for use as a blocking control in assays to test for specificity of this DDB2 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
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别名
- DDB2
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背景
- This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Synonyms: Polyclonal DDB2 antibody, Anti-DDB2 antibody, damage-specific DNA binding protein 2, 48kDa antibody, DDBB antibody, FLJ34321 antibody, UV-DDB2 antibody.
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途径
- DNA Damage Repair
抗原
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