CDK8 抗体 (C-Term)
Quick Overview for CDK8 抗体 (C-Term) (ABIN926004)
抗原
See all CDK8 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
交叉反应
- 小鼠, 大鼠, 犬, 斑马鱼, Frog, 小鸡
-
免疫原
- CDK8 antibody was raised in rabbit using the C terminal of CDK8 as the immunogen
-
-
-
-
应用备注
-
WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
CDK8 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CDK8 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
浓度
- Lot specific
-
缓冲液
- Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
-
-
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
-
别名
- CDK8
-
背景
- The protein encoded by CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. Synonyms: Polyclonal CDK8 antibody, Anti-CDK8 antibody, cyclin-dependent kinase 8 antibody.
-
途径
- Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
抗原
-