Caspase 3 抗体 (N-Term)
Quick Overview for Caspase 3 抗体 (N-Term) (ABIN925983)
抗原
See all Caspase 3 (CASP3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 大鼠, 猪, 犬, 兔, 牛
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免疫原
- CASP3 antibody was raised in rabbit using the N terminal of CASP3 as the immunogen
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应用备注
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WB: 5 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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CASP3 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CASP3 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Caspase 3 (CASP3)
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别名
- CASP3
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背景
- CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. Synonyms: Polyclonal CASP3 antibody, Anti-CASP3 antibody, caspase 3, apoptosis-related cysteine peptidase antibody.
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
抗原
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