DFFA 抗体 (N-Term)
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- 抗原 See all DFFA 抗体
- DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
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抗原表位
- N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DFFA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 大鼠
- 免疫原
- DFFA antibody was raised in rabbit using the N terminal of DFFA as the immunogen
- Top Product
- Discover our top product DFFA Primary Antibody
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- 应用备注
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WB: 5 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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DFFA Blocking Peptide, catalog no. 33R-5982, is also available for use as a blocking control in assays to test for specificity of this DFFA antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
- 别名
- DFFA (DFFA 产品)
- 别名
- DFF-45 antibody, DFF1 antibody, ICAD antibody, A330085O09Rik antibody, DFF35 antibody, Dff45 antibody, ICAD-L antibody, ICAD-S antibody, DFFA antibody, zgc:92229 antibody, DNA fragmentation factor subunit alpha antibody, DNA fragmentation factor, alpha subunit antibody, DNA fragmentation factor, 45kDa, alpha polypeptide antibody, DNA fragmentation factor, alpha polypeptide antibody, DFFA antibody, Dffa antibody, dffa antibody
- 背景
- Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Synonyms: Polyclonal DFFA antibody, Anti-DFFA antibody, DNA fragmentation factor, 45kDa, alpha polypeptide antibody, DFF-45 antibody, DFF1 antibody, Ion ChannelAD antibody.
- 途径
- Apoptosis, Caspase Cascade in Apoptosis
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