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TLR9 抗体 (C-Term)

This anti-TLR9 antibody is a 兔 多克隆 antibody detecting TLR9 in WB 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN920614
发货至: 中国

Quick Overview for TLR9 抗体 (C-Term) (ABIN920614)

抗原

See all TLR9 抗体
TLR9 (Toll-Like Receptor 9 (TLR9))

适用

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人, 小鼠

宿主

  • 64
  • 28
  • 6
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  • 2
  • 1

克隆类型

  • 70
  • 35
多克隆

标记

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This TLR9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC)
  • 抗原表位

    • 16
    • 10
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    • 6
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    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    • 1
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    C-Term

    产品特性

    Positive Control: Mouse spleen tissue lysate. Located in membrane, and highly expressed in spleen, lymph node, tonsil, and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.

    纯化方法

    Antigen Immunoaffinity purified

    免疫原

    Rabbit polyclonal TLR9 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human TLR9.

    亚型

    IgG
  • 应用备注

    Western blot: use at 1-2 µg/mL

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered saline with 0.02% sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    TLR9 (Toll-Like Receptor 9 (TLR9))

    背景

    Toll-like receptors (TRLs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. TLR9 forms a subfamily with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences and are localized in intracellular acidic compartments such as the phagolysosome. Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection, TRL9 is strictly dependent on MyD88. Synonyms:

    分子量

    115.8 kDa

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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