WNK4 抗体 (AbBy Fluor® 350)
Our Local Distributor
北京 101111
Quick Overview for WNK4 抗体 (AbBy Fluor® 350) (ABIN920035)
抗原
See all WNK4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human WNK4
-
亚型
- IgG
-
-
anti-WNK Lysine Deficient Protein Kinase 4 (WNK4) (AA 828-1106) antibody
WNK4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 4 (WNK4) (AA 1144-1243) antibodyWNK4 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-WNK Lysine Deficient Protein Kinase 4 (WNK4) (AA 351-450) antibodyWNK4 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 4 (WNK4) antibodyWNK4 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IF(IHC-P) 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
-
别名
- WNK4
-
背景
-
Synonyms: PHA 2B, PHA2B, PRKWNK 4, PRKWNK4, Protein kinase lysine deficient 4, Protein kinase with no lysine 4, Serine/threonine protein kinase WNK4, WNK lysine deficient protein kinase 4, WNK4_HUMAN.
Background: Regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation which appears to prevent membrane trafficking of SLC12A3. Also inhibits the renal K(+)channel, KCNJ1, via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis. WNK4 appears to act as a molecular switch that can vary the balance between NaCl reabsorption and K(+)secretion to maintain integrated homeostasis.
-
基因ID
- 65266
抗原
-
