VAV3 抗体 (AA 701-800) (AbBy Fluor® 350)
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Quick Overview for VAV3 抗体 (AA 701-800) (AbBy Fluor® 350) (ABIN919505)
抗原
See all VAV3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 701-800
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Dog,Cow,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse VAV3
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亚型
- IgG
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anti-Vav 3 Oncogene (VAV3) (AA 183-380) antibody
VAV3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (Internal Region) antibodyVerified VAV3 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 701-800) antibodyVAV3 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 560-680) antibodyVAV3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 398-583) antibodyVAV3 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 562-674) antibodyVAV3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) antibodyVAV3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 768-802), (C-Term) antibodyVAV3 适用: 人 WB 宿主: 兔 Polyclonal RB53259 unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- VAV3 (Vav 3 Oncogene (VAV3))
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别名
- VAV3
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背景
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Synonyms: Idd18.1, AA986410, A530094I06Rik, Guanine nucleotide exchange factor VAV3, VAV-3, Vav3
Background: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity). Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3-mediated adhesion. Does not affect integrin beta-1-mediated adhesion.
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基因ID
- 57257
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UniProt
- Q9R0C8
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途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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