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- 抗原 See all VAV3 抗体
- VAV3 (Vav 3 Oncogene (VAV3))
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抗原表位
- AA 562-674
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VAV3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Guanine nucleotide exchange factor VAV3 protein (562-674AA)
- 亚型
- IgG
- Top Product
- Discover our top product VAV3 Primary Antibody
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anti-Vav 3 Oncogene (VAV3) (AA 183-380) antibody
VAV3 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (Internal Region) antibodyVerified VAV3 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 701-800) antibodyVAV3 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 560-680) antibodyVAV3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 398-583) antibodyVAV3 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) antibodyVAV3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 768-802), (C-Term) antibodyVAV3 适用: 人 WB 宿主: 兔 Polyclonal RB53259 unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- VAV3 (Vav 3 Oncogene (VAV3))
- 别名
- VAV3 (VAV3 产品)
- 别名
- RGD1565941 antibody, A530094I06Rik antibody, AA986410 antibody, Idd18.1 antibody, vav guanine nucleotide exchange factor 3 antibody, vav 3 guanine nucleotide exchange factor antibody, vav 3 oncogene antibody, VAV3 antibody, Vav3 antibody
- 背景
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Background: Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2 (ITGB2)-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3 (ITGB3)-mediated adhesion. Does not affect integrin beta-1 (ITGB1)-mediated adhesion (By similarity).
Aliases: FLJ40431 antibody, Guanine nucleotide exchange factor VAV3 antibody, Protein vav 3 antibody, Protein vav3 antibody, RGD1565941 antibody, VAV 3 antibody, Vav 3 guanine nucleotide exchange factor antibody, VAV 3 oncogene antibody, VAV 3 protein antibody, VAV-3 antibody, Vav3 antibody, VAV3 oncogene antibody, VAV3 protein antibody, VAV3_HUMAN antibody
- UniProt
- Q9UKW4
- 途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
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