CRTC1 抗体 (AbBy Fluor® 555)
Quick Overview for CRTC1 抗体 (AbBy Fluor® 555) (ABIN918244)
抗原
See all CRTC1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human TORC1
-
亚型
- IgG
-
-
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (pSer151) antibody
CRTC1 适用: 人, 小鸡 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人 WB, IP, FACS, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1B5 unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (AA 1-248) antibodyCRTC1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (AA 553-634) antibodyCRTC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (AA 1-200) antibodyCRTC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
-
别名
- Torc1/Crtc1
-
背景
-
Synonyms: CREB regulated transcription coactivator 1, CRTC1, KIAA0616, MECT 1, Mucoepidermoid carcinoma translocated protein 1, also known as MucoEpidermoid Carcinoma Translocated 1, TORC1, Transducer of CREB protein 1, Transducer of regulated cAMP response element binding protein 1, WAMTP1.
Background: which activates transcription through both consensus and variant cAMP response element (CRE) sites. MECT1 does not appear to modulate CREB1 DNA-binding activity but enhances the interaction of CREB1 with TAF4/TAFII-130. MECT1 translocates with MAML2 (MasterMind-Like Protein 2) to yield a fusion oncogene: t(11,19) (q21,p13). This translocation occurs in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. The novel fusion product that results disrupts the Notch signaling pathway. The fusion protein consists of the N-terminus of MECT1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of MECT1 has been detected in a small number of mucoepidermoid carcinomas. Multiple isoforms have been reported for the MECT1 protein.
-
基因ID
- 23373
抗原
-
