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TNIP2 抗体 (AA 85-180) (Cy5.5)

This anti-TNIP2 antibody is a 兔 多克隆 antibody detecting TNIP2 in WB, IF (cc) 和 IF (p). Suitable for 人 和 大鼠.
产品编号 ABIN918186
发货至: 中国

Quick Overview for TNIP2 抗体 (AA 85-180) (Cy5.5) (ABIN918186)

抗原

See all TNIP2 抗体
TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

适用

  • 42
  • 25
  • 14
  • 1
人, 大鼠

宿主

  • 47

克隆类型

  • 47
多克隆

标记

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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This TNIP2 antibody is conjugated to Cy5.5

应用范围

  • 36
  • 16
  • 12
  • 12
  • 9
  • 8
  • 7
  • 5
  • 4
  • 3
  • 2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 85-180

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TNIP2/ABIN2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

    别名

    TNIP2

    背景

    Synonyms: KLIP, ABIN2, FLIP1, TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein, TNIP2

    Background: Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response, this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells, promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.

    基因ID

    79155

    UniProt

    Q8NFZ5

    途径

    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
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